Postdoctoral Position in RNA and Chemical Biology, immunotherapy, and Bioinformatics
University of California, San Diego
San Diego, California
Competitive salary and benefits
March 05 2020
Life Sciences, Physical Sciences, Health Sciences
Postdoctoral Position in RNA and Chemical Biology, Immunotherapy, and Bioinformatics
Available immediately for highly motivated recent Ph.Ds and/or MDs with strong training in biochemistry, bioinformatics, immunology, molecular and cell biology, virology, medicinal chemistry or chemical biology to participate in the following projects involving multidisciplinary teams of clinicians and basic science investigators: (a) investigate RNA biology mechanisms in immunotherapy and immune exhaustion; (b) identify epitranscriptomics roles in regulating cancer and host-pathogen interactions by preforming biochemical and genomics studies; (c) mechanisms of CAR T cell therapy relapses and side effects; (d) develop and employ human embryonic stem cell derived cerebral organoids and cancer stem cell based disease models; (e) identification and synthesis of new drug candidates to treat cancer and viral infections. Technologies employed in our projects include CRISPR, RNAi, single cell genomics (scRNA-seq and scATAC-seq), bioinformatics, proteomics, HT RNA-seq, gene editing, in vitro and vivo models for immunotherapy to treat cancer and viral infections, computational drug design and synthesis. Strong publication record and training to perform independent research are required for further consideration. We highly value and encourage applications from minority groups. For examples of our multidisciplinary work and technologies used in our work, see https://ranalab.ucsd.edu and representative publications: Cell Reports. 2020 Jan 28;30(4):969-983.e4. doi: 10.1016/j.celrep.2019.11.020.; EMBO J. 2019 Apr 15;38(8); MBio. 2019 Sep 24;10(5);Cancer Research, 2017Nov 15;77(22):6330-6339; Cell Stem Cell, 2016 Aug 4;19(2):258-65;Cell Host Microbe. 2016 Nov 9;20(5):666-673. doi: 10.1016/j.chom.2016.10.002; Cancer Research, 2016 Oct 1;76(19):5777-5787. Nature Microbiology, Article number: 16011 (2016) doi:10.1038/nmicrobiol.2016.11; J Med Chem, 2016 Aug 25;59(16):7677-82; Nat Rev Drug Discov. 2014, 622-38, Molecular Cell. 2014, 1005-19; Proc Natl Acad Sci USA. 2014,1002-7; Cell Stem Cell. 2014, 523-34; Cell Reports. 2014, 327-37; Genome Biol. 2013, R149, Nature Communications. 2012, 1085, EMBO J. 2011, 823-34, Molecular Cell,2009, 696, Nature Biotechnology, 2008, 1187-92, J Med Chem. 2012, 6328, ACS Med Chem Lett. 2012.
Successful Candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities. Applicants should send CV and names and addresses of three references email@example.com. Administrative Coordinator, Rana Laboratory, Division of Genetics, Moores Cancer Center, Institute for Genomic Medicine, and Center for Drug Discovery Innovation, University of California San Diego, La Jolla, California, USA.
The University of California is an Equal Opportunity/Affirmative Action Employer。 All qualified applicants will receive consideration for employment without regard to gender, race, color, religion, sex, national origin, disability, age or protected veteran's status。